Cell death by apoptosis is a feature of the rheumatoid nodule
نویسندگان
چکیده
منابع مشابه
Cell death by apoptosis is a feature of the rheumatoid nodule.
OBJECTIVE To examine the site and extent of apoptosis in the rheumatoid nodule and to determine whether this process make a significant contribution to the control of inflammation in the rheumatoid nodule as in other granulomas. METHODS Nine nodules and seven synovial membranes were examined by terminal deoxynucleotidyl transferase-mediated nick end labelling (TUNEL) in situ and a subset was ...
متن کاملSpinal cord compression by a rheumatoid nodule.
A case, believed to be unique, is reported of spinal cord compression due to an extradural rheumatoid nodule.
متن کاملIs cisplatin-induced cell death always produced by apoptosis?
It is generally accepted that DNA damage and subsequent induction of apoptosis may be the primary cytotoxic mechanism of cisplatin and other DNA-binding antitumor drugs (Fisher,1994). Because the final step of apoptosis is characterized by morphological changes in the nucleus, the death signals of the execution phase must be transmitted from the cytoplasm to the nucleus. Thus, the recognition a...
متن کاملtranslating allusive devices:a survey of a portrait of the artist as a young man by james joyce
تلمیح یکی از عناصری است که تقریباً در همه ی متون ادبی یافت و باعث ایجاد شکاف های فرهنگی می شود. در این تحقیق به عنوان شکلی از بینامتنیت در ترجمه مورد توجه قرار می گیرد. تلاش شده است تا راهکارهای مترجمان برای ترجمه چهار نوع اسامی خاص و عبارات کلیدی تلمیحی (مذهبی، سیاسی، تاریخی و اسطوره ای) موجود در رمانِ چهره مرد هنرمند در جوانی به فارسی بررسی شود. این تحقیق مقایسه ای بر اساس راهکارهای ترجمه تلمیح...
15 صفحه اولApoptosis is not the major death mechanism induced by celecoxib on rheumatoid arthritis synovial fibroblasts
Synovial hyperplasia in rheumatoid arthritis (RA) has been associated with apoptosis deficiency of RA fibroblast-like synoviocytes (FLSs). Celecoxib is a non-steroidal anti-inflammatory drug that has been demonstrated to induce apoptosis in some cellular systems. We have therefore examined the dose- and time-dependent effects of celecoxib on RA FLS viability. Treatment of RA FLSs with celecoxib...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 2003
ISSN: 0003-4967
DOI: 10.1136/ard.62.1.77